Peng Li, Donghua Liu, Lei Miao, Chunxi Liu, Xiaoli Sun, Yongjun Liu, Na ZhangSchool of Pharmaceutical Science, Shandong University, Jinan, Shandong, People’s Republic of ChinaBackground: The success of gene therapy asks for the Vegan Protein Powder development of multifunctional vectors that could overcome various gene delivery barriers,
Monoclonal antibodies constructed from COVID-19 convalescent memory B cells exhibit potent binding activity to MERS-CoV spike S2 subunit and other human coronaviruses
IntroductionThe Middle East respiratory syndrome coronavirus (MERS-CoV) and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are two highly contagious coronaviruses causing MERS and COVID-19, respectively, without an effective antiviral drug and a long-lasting vaccine.Approaches for diagnosis, therapeutics, prevention, etc., particu
Management and prediction of immune-related adverse events for PD1/PDL-1 immunotherapy in colorectal cancer
Programmed cell death protein (PD-1) is an important immunosuppressive molecule, which can inhibit interaction between PD-1 and its ligand PD-L1, further enhancing the T cell response and anti-tumor activity, which is called immune checkpoint blockade.Immunotherapy, represented by 617 immune checkpoint inhibitors, has opened up a new era of tumor t
Obsessive-Compulsive Disorder in children. A case report
Introduction We present a 9-year-old girl with celiac disease who attends a Health Center referred by her pediatrician for rituals.Her mother describes rituals from early childhood that have been intensified by the death of her grandmother from pancreatic cancer.Since then, thoughts of gluten contamination and behaviors aimed at avoiding such conta